Frontiers in Cell Signaling and Gene Regulation (SignGene) is a joint international research school of the Max Delbrück Center for Molecular Medicine (MDC), the HU and the Charité in Berlin, and our partners in Israel, the Technion, Israel Institute of Technology in Haifa and the Hebrew University of Jerusalem. Funded by the Helmholtz Association, the program covers the fields of cell and molecular biology, biophysics and bioengineering.

The research focuses on unraveling the mechanisms that govern the differentiation and physiological functions of normal cells with the goal of understanding the pathological processes underlying diseases such as cancer. The following issues are thereby addressed:

Cell Signaling: How do cells respond to changes in their environment and relay this information into cellular decisions?

Gene Regulation: What are the basic mechanisms controlling gene expression; how does this information feed into global gene expression networks?

Quantitative Biology: How does the structure of proteins determine their functions? Can we build computational models to understand complex cellular processes?

Exchange visits in a partnering lab abroad, annual scientific symposia and winter schools are some of the aspects of the 3-year training program.

Prof. Dr Claus Scheidereit Prof. Amit Meller, PhD Prof. Yaakov Nahmias, PhD Dr Sabine Loewer Humboldt-Universität zu Berlin programme

Cell Signaling, Gene Regulation, Molecular Cell Medicine, biomedical sciences